cart phone email location menu facebook instagram twitter youtube

MycoMIND - Brain Cell Optimizer

Buy now Explore

MycoMIND - Brain Cell Optimizer

- +


Organic Lion's Mane Mushroom

Lion’s Mane is a nootropic mushroom that has been used Japan for thousands of years. Recently, western science has confirmed its neuroregenerative properties and role in enhancing cognition.


BioPQQ™ is the purest and most potent source of pyrroloquinoline quinone (PQQ), a polyphenol that is an exceptional antioxidant and cell regulator that promotes mitochondrial survival, growth, and function.

The brain loses about 200,000 brain cells every day

Certain things can greatly accelerating this loss, including too much stress, alcohol, smoking, high blood pressure, and physical inactivity.

Fortunately no matter how many brain cells (or neurons) you’ve lost in the past (or are still losing), your brain has the ability to grow new brain cells through a process called neurogenesis.  Your brain needs a protein called Nerve Growth Factor (NGF) for this to happen.

If you don’t have a sufficient supply of NGF to generate new brain cells the result could be brain fog, the inability to concentrate, and memory lapses.

Nerve Growth Factor is essential for brain health and neuroplasticity

The discovery of NGF by Rita Levi-Montalcini and Stanley Cohen in 1951 was one of the greatest breakthroughs in modern science, winning a Nobel Prize in 1986.  Prior to its discover it was believed that brain cells could not recover or regrow after being damaged or killed.

NGF has now been studied extensively and shown to be one of the primary building blocks for overall brain health and neuroplasticity.  It is essential for the growth and survival of neurons.  The more neurons that you have and the better their health, the more efficiently you can rely signals in your brain.

In 1991 Dr. Kawagishi discovered that Lion’s Mane (Hericium erinaceus) contain hericenones and erinacines that stimulate the production of NGF in the human brain.  Since then in vitro and in vivo studies have confirmed these findings.  A recent human study showed that Lion’s Mane significantly increased the cognitive function of individuals with mild cognitive decline.

Supercharge your Mitochondria - the powerhouse of the cell

Mitochondria helps generate over 90% of the energy that your body uses on a daily basis.  Your brain requires the greatest amount of energy compared of any other organ, so optimizing your mitochondrial health is vital for improving brain function.

Pyrroloquinoline quinone (PQQ) is a cellular nutrient that can promote Mitochondrial Biogenesis, the creation of new mitochondrial.  This supercharges the survival, growth, and function of mitochondrial leading to increased mental capacity. PQQ has also been shown to support NGF.  

BioPQQ is the purest and most potent source of PQQ and is featured in the MycoMIND™ formula.  

MycoMIND - the most essential daily nootropic

The combination of Lion’s Mane Mushroom and BioPQQ™ create a foundation for high-level mental performance.  The ability to maintain and grow new neurons and mitochondria is necessary for all mental tasks, making MycoMIND™ the most essential daily nootropic.

Brain Cell Optimizer

SUGGESTED USE: Take 2 capsules 1 to 2 times per day for brain health and mental sharpness, or as directed by a healthcare practitioner.

U.S.A manufactured in a cGMP facility.  Natural Stacks proudly uses only the highest quality ingredients.

Ingredients Naturally Free of: Gluten, Dairy, Soy.

1 Certified Organic.

2 As BioPQQ. BioPQQ is a trademark of MGC (Japan)

Organic Lion’s Mane Mushroom Extract

Lion’s Mane mushroom contains hericenones and erinacines which activates Nerve Growth Factor (NGF) for the growth of new neurons and the survival of existing neurons.  MycoMIND™ features organic lion’s mane mushroom extract from NAMMEX (North American Medicinal Mushroom Extracts). It is water extracted and lab tested to contain >30% Beta-D-glucans and <3% starch.


BioPQQ™ is the purest and most potent source of pyrroloquinoline quinone (PQQ), a polyphenol that is an exceptional antioxidant and cell regulator that promotes mitochondrial survival, growth, and function.  

Lion’s Mane

The original discovery of Lion’s Mane’s ability to increase Nerve Growth Factor (NGF) occurred in 1991 and is credited to Japanese scientists, Dr. Kawagishi. This discovery presented a massive paradigm shift in the way science looks at brain cells. No longer a finite number that decreases over our lifespan, entire fields of scientific research have since been devoted to maintaining - even increasing - brain cell counts for enhanced cognitive function and longevity.

Since that time, numerous studies have confirmed that this naturally occurring mushroom contains active compounds that stimulate NGF synthesis in human cells and promotes neurite outgrowth via activation of the JNK pathway (Jun amino-terminal kinase) This was proven in vivo. When they fed mice with Lions Mane powder there was an increase in the level of NGF mRNA expression in the hippocampus. [3,4]

A study published in the September 2014 edition of the International Journal of Molecular Science confirmed that Lion’s Mane contains a compound known as Erinacine A that effectively scavenges free radicals, inhibiting inflammation and helps repair injured brain and nerve cells. [5]

Based on a 2010 study published in Biomedical Research, Lion’s Mane seems to decrease anxiety and depression symptoms. [6]

According to a 2008 Japanese study, Lion’s Mane seems to halt and reverse (increased score on cognitive function scale) cognitive decline in 50-80 year old Japanese men and women who suffered from mild cognitive impairment. The effect weren’t permanent and the scores declined after 4 weeks of stopping the ingestion of Lion’s Mane. [7]


Pyrroloquinoline quinone, or PQQ for short, is a coenzyme that was discovered in 1979. PQQ is involved in many of the body’s natural metabolic processes and PQQ supplementation has been shown in studies to provide neuroprotective activity, anti-oxidative activity, and mitochondrial biogenesis.

Our source, BioPQQ is the industry leader for pyrroloquinoline quinone. Simply put, PQQ helps us create new mitochondria. [8]

In recent years, a substantial body of evidence has underscored the importance of mitochondrial function in maintaining energy balance, minimizing oxidative stress and promoting longevity. Mitochondrial function has been examined in many aspects, including metabolic, neural and age-related conditions. PQQ deficiency decreases the size, number and function of mitochondria in rodents, and supplementation reverses these effects.[9,10,11]

Supplementation with PQQ has been shown to improve memory and reasoning, while more studies indicate that PQQ offers neuro-protective properties via reduction of oxidative damage. In a randomized, double-blind study of 71 middle aged individuals, PQQ supplementation over 12 weeks significantly improved short term memory and demonstrated the ability to prevent memory loss. [12,13,14]

In 2012, Japanese researchers performed the first human study examining the effect of BioPQQ on stress, fatigue, and sleep. They concluded that supplementing with PQQ improved sleep, leading to reduced negative mental states, relief of fatigue and rise of positive mood. Other important conclusions from this study were that “mood also was improved by diminishing feelings of fatigue, and improved measures of appetite, sleep, pain and obsession with no adverse effects.” [15]

A 2016 study examining the impact of BioPQQ using near-infrared spectrometry (NIRS) found that cerebral blood flow in the prefrontal cortex was increased by the administration of PQQ. “The results suggest that PQQ can prevent reduction of brain function in aged persons, especially in attention and working memory.” [16]

  1. Kawagishi, H. Lion’s Mane: The Anti-Dementia Effect of Lion's Mane Mushroom and it’s Clinical Application. Townsend Letter for Doctors and Patients. APRIL 2004
  2. Mori K. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial.Phytother Res. 2009 Mar;23(3):367-72. doi: 10.1002/ptr.2634.
  3. Mori K. Nerve growth factor-inducing activity of Hericium erinaceus in 1321N1 human astrocytoma cells. Biol Pharm Bull. 2008 Sep;31(9):1727-32.
  4. Lai PL. Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. Int J Med Mushrooms. 2013;15(6):539-54.
  5. Lee K-F, Chen J-H, Teng C-C, et al. Protective Effects of Hericium erinaceus Mycelium and Its Isolated Erinacine A against Ischemia-Injury-Induced Neuronal Cell Death via the Inhibition of iNOS/p38 MAPK and Nitrotyrosine. International Journal of Molecular Sciences. 2014;15(9):15073-15089. doi:10.3390/ijms150915073.
  6. Nagano M. Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Biomed Res. 2010 Aug;31(4):231-7.
  7. Mori K. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial.Phytother Res. 2009 Mar;23(3):367-72. doi: 10.1002/ptr.2634.
  8. Chowanadisai W. Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression. J Biol Chem. 2010 Jan 1;285(1):142-52. doi: 10.1074/jbc.M109.030130. Epub 2009 Oct 27.
  9. Stites T, Storms D, Bauerly K, Mah J, et al. Pyrroloquinoline quinone modulates mitochondrial quantity and function in mice. J Nutr. 2006;136(2):390-6.
  10. Bauerly KA, Storms DH, Harris CB, Hajizadeh S, et al. Pyrroloquinoline quinone nutritional status alters lysine metabolism and modulates mitochondrial DNA content in the mouse and rat. Biochim Biophys Acta. 2006;1760(11):1741-8.
  11. Zhu BQ, Simonis U, Cecchini G, Zhou HZ, et al. Comparison of pyrroloquinoline quinone and/or metoprolol on myocardial infarct size and mitochondrial damage in a rat model of ischemia/reperfusion injury. J Cardiovasc Pharmacol Ther. 2006;11(2):119-28.
  12. He B. The roles of PI3K/Akt pathway in proliferation of Schwann cells promoted by pyrroloquinoline quinone. Zhonghua Zheng Xing Wai Ke Za Zhi. 2010 Jan;26(1):53-6.
  13. Ohwada K, Takeda H, Yamazaki M, Isogai H, et al. Pyrroloquinoline quinone (PQQ) prevents cognitive deficit caused by oxidative stress in rats. J Clin Biochem Nutr. 2008;42:29-34]
  14. Nakano M, Ubukata K, Yamamoto T, Yamaguchi H. Effect of pyrroloquinoline quinone (PQQ) on mental status of middle-aged and elderly persons. FOOD Style 21 2009;13(7):50-53.
  15. Nakano, M. Effects of Oral Supplementation with Pyrroloquinoline Quinone on Stress, Fatigue, and Sleep. Functional Foods in Health and Disease 2012, 2(8):307-324 Page 307 of 324
  16. Itoh, Y. Effect of the Antioxidant Supplement Pyrroloquinoline Quinone Disodium Salt (BioPQQ™) on Cognitive Functions. Adv Exp Med Biol. 2016;876:319-25.

Dedication to quality

Natural Stacks formulas contain premium ingredients which are carefully selected solely on the basis of quality and purity. We actively seek out the most bioavailable forms of each ingredient, and avoid the cheap synthetic forms used by the majority of supplement companies.

Learn More

Open source

Most companies use "proprietary blends" so they don't have to tell you the amount of each ingredient in their formulas. It's a shady and sometimes dangerous practice. At Natural Stacks we believe it's your right to know exactly what you're putting into your body. We proudly publish our innovative formulas in an open source format.

Learn More

Money back guarantee

If for whatever reason you're unsatisfied with your Natural Stacks, you can return the product within 30 days for a full refund. We also provide actionable tips on our blog and support in our forum for you to maximize your performance with our premium products.

Learn More